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Small extracellular vesicles derived from solid tumors inhibit the efficacy of CAR-T cellsChimeric antigen receptor T-cell ( CAR-T ) therapy has shown significant efficacy in the treatment of hematopoietic tumors. However, their effectiveness in trea...05-15 -
NKG2D-CAR T cell anti-aging researchThe reason why humans die is that exhausted tissues cannot renew themselves forever, and the ability of cells to divide is also limited. Aging is a problem that...05-15 -
CAR T targeting intracellular oncoproteinsCAR - T cell tumor immunotherapy has demonstrated strong anti-tumor efficacy in hematological tumors such as leukemia, but its application in the field of solid...05-15 -
Limitations and breakthrough directions of CAR-T in the treatment of solid tumorsThe incidence and mortality of cancer continue to increase, but effective treatments have not yet been found. Traditional therapies, including surgery, radiothe...05-15 -
Study on CD123-targeted CAR-T cells for the treatment of AMLCAR-T cell therapy is an immunotherapy method that uses genetic engineering technology to modify human T cells so that they can specifically recognize and kill ...05-15 -
CRISPR screening reveals the role of BHLHE40 in mimicking CD8+ T cell exhaustion in vitroT cell exhaustion is a state in which T cells lose function under long-term stimulation of chronic infection and cancer. Its main manifestations are: reduced ...05-15
