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Research progress of universal cell therapyCAR-T cell therapy brings new hope to cancer patients with its unique targeted therapy. The 10 CAR-T drugs currently on the market are mainly autologous CAR-T c...04-08 -
Mammalian gene expression vectorsIn the biomedical field, the use of conventional transfection to transfer plasmid vectors into mammalian cells is the most widely used method.Although many more...04-03 -
Metabolic challenges in CAR-T cell therapyCAR-T cell therapy has already shown great success in treating advanced hematologic malignancies. However, its efficacy in solid tumors has been unsatisfactory,...04-08 -
Chimeric vectorsAdeno-associated virus(AAV) is widely used in gene transduction experiments both in vivo and in vitro. AAV can infect a large variety of mammalian cells, produc...04-08 -
A new strategy to enhance anti-tumor activity and persistence: reducing CAR-T cell methylation levelDNA methylation refers to the change of specific bases in the DNA sequence at the C-5 position of cytosine, the N-6 position of adenine and the chromium positio...04-08 -
VSV virus vectorVesicular stomatitis virus (VSV) vectors are widely used in studying the invasion of viral particles into host cells, identifying cell surface receptors that me...04-08
